[Frontiers in Bioscience 3, e123-132 ,July 23, 1998]
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MYCOBACTERIAL PATHOGENESIS: A HISTORICAL PERSPECTIVE

Frank M. Collins

Laboratory of Mycobacteria, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD.

Received 5/6/98 Accepted 5/21/98

TABLE OF CONTENTS

1. Abstract
2. Introduction
3.Consumption, Phthisis, scrofulosis, Pott’s disease or the White plague
4. Bacille de Calmette-Guerin (BCG) vaccine development
5. Virulence factors associated with the tubercle bacillus
6. Anti-tuberculosis vaccines and protection against aerogenic infection
7. Perspectives in pathogenesis
8. References
9. Entire manuscript

Key words: Tuberculosis, Pathogenesis, Immunity

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